Antihistamines – Hydroxyzine hydrochloride

Hydroxyzine hydrochloride is an antihistamine that is used for treating allergic and inflammatory skin conditions – it can be used in the treatment of interstitial cystitis/painful bladder syndrome as it blocks the chemicals that can cause inflammation.

People with IC/PBS should normally see an improvement within a short space of time if hydroxyzine hydrochloride is used as treatment.

Hydroxyzine hydrochloride is not suitable for everyone so it’s important that the person prescribing this medicine knows your full medical history.

You may not be suitable for this medication if you:

  • are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
  • have bladder problems
  • have kidney problems

Side Effects of Hydroxyzine Hydrochloride

Everyone’s reaction to a medicine is different. You may experience some of the side effects listed below or none at all. If you are having problems with this medicine, it’s important to tell your GP immediately.

Possible side effects of taking Hydroxyzine hydrochloride are:

  • confusion
  • convulsions
  • dry mouth
  • feeling dizzy
  • feeling drowsy
  • headaches
  • motor problems
  • reduced alertness
  • tremors
  • urinary retention
  • weakness

If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist, nurse or call NHS non-emergency number on 111 (You should use the NHS 111 service if you urgently need medical help or advice but it’s not a life-threatening situation)