Colorectal Cancer Clinical Trials – SIRT for Liver Metastases

BTG EPOCH Clinical Trial Study for Metastatic Colorectal Cancer

The following video is exclusively intended to support patient education as it relates only to the EPOCH Clinical Trial. It is not intended, nor is it to be used, to market the medical products discussed in the video.

If you are currently receiving chemotherapy treatment for metastatic colorectal cancer with mets to the liver only, then information regarding a clinical trial involving SIRT (Selective Internal Radiation Therapy) may be of interest to you. The video above contains details on how the treatment works and what the criteria is to join the trial. Discuss your eligibility with your oncologist or follow the link below for further information.

Epoch Logo

The EPOCH study is a randomised controlled trial that aims to assess the safety and efficacy of Selective Internal Radiation Therapy (SIRT) for patients with metastatic colorectal cancer (mCRC) that has spread to the liver. Patients are randomised to receive either:

  • Second-line chemotherapy alone
  • Second-line chemotherapy with SIRT

As SIRT only treats patients with liver tumours, the trial only accept patients whose cancer has the following characteristics:

  • Stable primary colon or rectal cancer
  • Liver metastases only
  • Patients who have received a line of chemotherapy with either oxaliplatin or irinotecan

If you are interested in participating, please contact your physician about the possibility of joining the trial. Your treating physician will assess your suitability for joining the trial, and refer you to the nearest participating centre. Otherwise, you can get into contact with members of the trial team directly – the details of which are available by clicking the button below.


BTG, the sponsor of the EPOCH study, takes the privacy patient information very seriously. BTG will ensure patient information is securely collected, stored and used exclusively for EPOCH clinical trial activities. For more information on BTG’s commitment to protecting personal data, please read BTG’s at https://btgplc.com/responsibility/global-privacy-policy/. You may also contact the Data Protection Officer at BTG at dpo@btgplc.com.